• Chinese Science Citation Database (CSCD) Source Journals
  • A Guide to the Core Journals of China
  • Top 100 Sci-Tech Journals of Chinese Universities
  • Chinese Science and Technical Core Journals
  • China Agriculture and Forestry Core Journals (Category A)
Advanced Search
Jialin LIU, Conghui JI, Lijiao GAO, et al. Process Optimization of β-Cyclodextrin Inclusion Complex of Royal Jelly and Its Stability Investigation[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2018, 33(6): 1113-1119. DOI: 10.12101/j.issn.1004-390X(n).201804014
Citation: Jialin LIU, Conghui JI, Lijiao GAO, et al. Process Optimization of β-Cyclodextrin Inclusion Complex of Royal Jelly and Its Stability Investigation[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2018, 33(6): 1113-1119. DOI: 10.12101/j.issn.1004-390X(n).201804014
shu

Process Optimization of β-Cyclodextrin Inclusion Complex of Royal Jelly and Its Stability Investigation

  • Chongqing Academy of Animal Sciences, Chongqing 402460, China

More Information
  • Received Date: April 07, 2018
  • Revised Date: May 10, 2018
  • Available Online: November 19, 2018
  • Published Date: October 31, 2018
    Graphical Abstract
    • Abstract
  • Purpose To evaluate the efficiency of inclusion complex of royal jelly by β-cyclodextrin (β-CD).
    Method Single factor experiment and orthogonal test were conducted, as well as investigated the qualities of the inclusion complex.
    Results Temperature, pH, β-CD amount and reaction time significantly affected the soluble protein content of inclusion complex; the optimum condition of inclusion process was 27 ℃, pH 8.7, β-CD 12.50 mg/mL and 5 h. Acid, alkali and heat treatment didn’t reduce the soluble protein content of inclusion complex (P>0.05). Storing at −20 ℃ and 4 ℃ stabilized the complex quality (P>0.05). The solubility of inclusion complex was significantly higher than royal jelly (P<0.01).
    Conclusion β-CD inclusion increased considerably the stability and solubility of royal jelly.
    • FullText(HTML)
    • References (24)
  • [1]
    KAMAKURA M. Royalactin induces queen differentiation in honeybees[J]. Nature, 2011, 473(7348): 478. DOI: 10.1038/nature10093.
    [2]
    蔡柳, 林亲录. 蜂王浆的研究进展[J]. 中国食物与营养, 2007(8): 19. DOI: 10.3969/j.issn.1006-9577.2007.08.006
    [3]
    张智武, 单斌, 彭文君, 等. 蜂王浆中水溶性蛋白质和活性肽的研究进展[J]. 食品研究与开发, 2007, 28(10): 33. DOI: 10.3969/j.issn.1005-6521.2007.10.011
    [4]
    黄盟盟, 薄文飞, 张林军, 等. 蜂王浆的主要活性成分及其保健作用[J]. 中国酿造, 2009, 28(2): 152. DOI: 10.3969/j.issn.0254-5071.2009.02.050
    [5]
    侯春生, 骆浩文. 蜂王浆主要功能、有效化学成分及在食品工业中的应用[J]. 广东农业科学, 2008(12): 121. DOI: 10.3969/j.issn.1004-874X.2008.12.045
    [6]
    孙平, 李虎臣, 颜慧, 等. 蜂王浆蛋白多肽及其生物活性研究进展[J]. 食品研究与开发, 2011, 32(8): 182. DOI: 10.3969/j.issn.1005-6521.2011.08.054
    [7]
    KAMAKURA M, SUENOBU N, FUKUSHIMA M. Fifty-seven-kDa protein in royal jelly enhances proliferation of primary cultured rat hepatocytes and increases albumin production in the absence of serum[J]. Biochemical and Biophysical Research Communications, 2001, 282(4): 856. DOI: 10.1006/bbrc.2001.4656.
    [8]
    KIMURA M, KIMURA Y, TSUMURA K, et al. 350-kDa royal jelly glycoprotein (apisin), which stimulates proliferation of human monocytes, bears the beta1-3 galactosylated N-glycan: analysis of the N-glycosylation site[J]. Bioscience Biotechnology Biochemistry, 2003, 67(9): 2055. DOI: 10.1271/bbb.67.2055.
    [9]
    OKAMOTO I, TANIGUCHI Y, KUNIKATA T, et al. Major royal jelly protein 3 modulates immune responses in vitro and in vivo[J]. Life Sciences, 2003, 73(16): 2029. DOI: 10.1016/S0024-3205(03)00562-9.
    [10]
    张映, 姜玉锁, 牛建英. 蜂王浆中超氧化物歧化酶活力测定[J]. 山西农业大学学报, 1996, 16(3): 267. DOI: 10.13842/j.cnki.issn1671-8151.1996.03.016
    [11]
    闵丽娥, 李佳, 刘克武, 等. 意蜂蜂王浆超氧化物歧化酶的分离纯化及部分性质[J]. 昆虫学报, 2004, 47(2): 171. DOI: 10.716380/j.kcxb.2004.02.006
    [12]
    BILIKOVA K, HUANG S C, LIN I P, et al. Structure and antimicrobial activity relationship of royalisin, an antimicrobial peptide from royal jelly of Apis mellifera[J]. Peptides, 2015, 68: 190. DOI: 10.1016/j.peptides.2015.03.001.
    [13]
    SHEN L R, LIU D D, LI M L, et al. Mechanism of action of recombinant Acc-royalisin from royal jelly of Asian honeybee against gram-positive bacteria[J]. PLoS One, 2012, 7(10): e47194. DOI: 10.1371/journal.pone.0047194.
    [14]
    孙晓军, 杨晓慧, 李桂明, 等. 蜂王浆贮藏过程中品质变化的研究[J]. 山东农业科学, 2015, 47(5): 103. DOI: 10.14083/j.issn.1001-4942.2015.05.029
    [15]
    张娟, 赵利, 魏丽, 等. 贮藏温度和时间对蜂王浆水溶性蛋白质的影响[J]. 食品与生物技术学报, 2008, 27(4): 58. DOI: 10.3321/j.issn:1673-1689.2008.04.013
    [16]
    张娟, 赵利, 刘建涛, 等. 蜂王浆中生物活性物质贮藏稳定性的研究进展[J]. 食品科学, 2006, 27(11): 530. DOI: 10.3321/j.issn:1002-6630.2006.11.132
    [17]
    王佳, 冯建国, 马超, 等. 环糊精包合技术及其在农药制剂加工中的应用[J]. 农药学学报, 2013, 15(1): 23. DOI: 10.3969/j.issn.1008-7303.2013.01.03
    [18]
    张雯文, 马建武, 任和, 等. 环糊精包合技术及其在食品工业中的应用进展[J]. 食品工业, 2014, 35(9): 256
    [19]
    JUN S W, KIM M S, KIM J S, et al. Preparation and characterization of simvastatin/hydroxypropyl-β-cyclodextrin inclusion complex using supercritical antisolvent (SAS) process[J]. European Journal of Pharmaceutics and Biopharmaceutics, 2007, 66(3): 413. DOI: 10.1016/j.ejpb.2006.11.013.
    [20]
    KRINGEL D H, ANTUNES M D, KLEIN B, et al. Production, characterization, and stability of orange or eucalyptus essential oil/β-cyclodextrin inclusion complex[J]. Journal of Food Science, 2017, 82(11): 2598. DOI: 10.1111/1750-3841.13923.
    [21]
    沈海民, 纪红兵, 武宏科, 等. β-环糊精的固载及其应用最新研究进展[J]. 有机化学, 2014, 34(8): 1554. DOI: 10.6023/cjoc201402024
    [22]
    刘佳霖, 梁明荣, 高丽娇, 等. 酶解与包合技术制备水溶性蜂王浆[J]. 云南农业大学学报(自然科学), 2015, 30(2): 234. DOI: 10.16211/j.issn.1004-390X(n).2015.02.011
    [23]
    戚向阳, 吴丽琴. 酶改性蛋白制备水溶性蜂王浆的研究[J]. 食品工业科技, 2009, 30(4): 146. DOI: 10.13386/j.issn1002-0306.2009.04.089
    [24]
    戚向阳. 水溶性蜂王浆酶法制备条件的优化及其特性的研究[J]. 中国食品学报, 2009, 9(4): 157. DOI: 10.3969/j.issn.1009-7848.2009.04.025
    • Related Articles

  • Related Articles

    [1]XIAO Mingxia, HUANG Zunxi, PHOUTHAPANE Vanhnaseng, ZHU Xiaodong, YUAN Lihong, CHENG Zhibin. Effects of the Stability of Clostridium butyricum Additive on Intestinal Microflora Regulation in Broiler Chickens[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2024, 39(6): 75-81. DOI: 10.12101/j.issn.1004-390X(n).202206076
    [2]ZHAO Linlin, WU Zhixiang, SUN Rui, YANG Chuan, FU Qingmao, TANG Mengqi. Soil Organic Carbon Components and Influencing Factors of Rubber Plantations of Different Ages in Qiongzhong, Hainan[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2023, 38(5): 886-893. DOI: 10.12101/j.issn.1004-390X(n).202204033
    [3]Ying LI, Yan GUO, Xinfang ZHANG, Shuhang ZHANG, Guangpeng WANG. Study on the Variation Characteristics of Soluble Solid Content in Chestnut at Post-ripening Stage in Chinese Main Producing Areas[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2022, 37(4): 655-662. DOI: 10.12101/j.issn.1004-390X(n).202201006
    [4]Yanhui GUO, Yi YANG, Zhiquan YANG, Zhijun KONG. Fuzzy Comprehensive Analysis on the Slope Stability of Jinjiang Farmland Irrigation Canal[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2021, 36(5): 905-911. DOI: 10.12101/j.issn.1004-390X(n).202008066
    [5]Shoudong BI, Guangjing QIAN, Xueyu SONG, Shuping ZHANG, Yan YU, Shang LI, Xiazhi ZHOU, Yunding ZOU. Analysis on the Species Diversity of Arthropod Communities in Different Tea Gardens[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2020, 35(2): 206-212. DOI: 10.12101/j.issn.1004-390X(n).201805069
    [6]Jiahe DAI, Xuanfei LUO, Chongying SHI, Cunchao ZHAO, Jun SHENG, Yang TIAN, Liang TAO. Optimization of Extraction Process for Water-soluble Protein of Moringa oleifera Leaves by Response Surface Methodology[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2020, 35(1): 130-138. DOI: 10.12101/j.issn.1004-390X(n).201805050
    [7]ZHAO Jiacheng, GAO Hui, WANG Hui, LIU Jing, WANG Yuzhen, LIN Hongjia, CUI Yuxiang, HUA Yikun. Effects of Cutting Width of Tobacco on Cut Tobacco Structure and its Distribution Stability[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2017, 32(4): 668-677. DOI: 10.16211/j.issn.1004-390X(n).2017.04.015
    [8]YANG Yang, GAO Hui, WANG Hui, ZHAO Jiacheng, JIAO Jun, GAO Zhanyong, WANG Yuzhen, MA Xiaolong, YANG Jingjin. Effects of Combination of Different Width Cut Tobacco on Cigarette Physical Indexes and Its Comprehensive Stability[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2017, 32(3): 488-497. DOI: 10.16211/j.issn.1004-390X(n).2017.03.014
    [9]CHENG Shang, YIN Suhui, LIU Jialin, GAO Lijiao, CAO Lan, JIE Huadong, DAI Rongguo, LUO Wenhua, XIE Hua. Study on the Hydrolysis of Royal Jelly Protein by Proteinase K[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2016, 31(2): 288-293. DOI: 10.16211/j.issn.1004-390X(n).2016.02.015
    [10]LIU Jialin, LIANG Mingrong, GAO Lijiao, CAO Lan, DAI Rongguo, LUO Wenhua, JIANG Yu, LIU Qi, XIE Huadong, CHENG Shang. Water-soluble Royal Jelly Produced by Enzymolysis and Inclusion[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2015, 30(2): 234-238. DOI: 10.16211/j.issn.1004-390X(n).2015.02.011

  • Cited by

    Periodical cited type(2)

    1. 彭天英，林一婷，刘赛文，殷志红. 樟脑环糊精包合物的制备研究. 湖南城市学院学报(自然科学版). 2025(01): 74-78 .
    2. 申雨苗，王倩，郭瑜，牛佳琪，孙萌萌. 基于环糊精及其衍生物的递送体系在食品领域的研究进展. 食品工业科技. 2022(24): 496-505 .

    Other cited types(0)

Catalog

    Get Citation
    PDF
    XML
    Article views (1935) PDF downloads (14) Cited by(2)
    Turn off MathJax
    Article Contents
    Abstract
    References
    Related Articles
    • Copyright © Journal of Yunnan Agricultural University Editorial Department
    • Address: Room 108, Adult Education Building, Yunnan Agricultural University, No. 95 Heijin Road, Kunming, Yunnan Postal Code: 650201
    • Tel: +86-871-65227711 E-mail: ynauzkxb@foxmail.com

    Supported by: Beijing Renhe Information Technology Co., Ltd.

    Return