Abstract: UPI questionnaire survey displays that female students psychological abnormalities are serious than male students in Yunnan agricultural university. The causes areanalyzed by compared nearly three years of UPI investigation data, used the psychology theory from the aspects of physiology, psychology, social environment. Aiming at theseproblems, this paper puts forward the countermeasures from the aspects of psychological counseling, school education, and social support, which are important for female collegestudents mental health.