Abstract: In order to improve the pertinence andeffect of Marx doctrine principle curriculum，on the basis of drawing some work experiences of people working in the same field，this paper analyzes thefeasibility of research-based teaching in Marx doctrine principle curriculum，combining with the author's own teaching practice, and elaborates how to carryout the curriculum，such as discussion teaching method,comparative teaching method and practice teaching method，at last points out some problems needing to deal with.