Abstract: Yunnan has faced the worst drought in a century in 2010, which brings the serious influence to peoples living and production，and the drought posed a serious threat to industrial and agricultural production. Considering that drought is frequent in winter and spring in Yunnan, the authors of this paper suggests that selective breeding of droughtresistance crops, development of key cultural techniques for drought resistant,demonstrations and applications of biodiversity intercrop and crosscultivation technique of scientific and technological services for agricultural universities are the most important ways to fight the drought.