Abstract: The endemic theory was an important traditional agronomy ideology, which was due to the introduction of crops from one place to another. With the extensive introductions from the local places and promotions technology, late Qing dynasty become the most important development and practice period about the endemic theory of sericulture. Silkworm books written by gentrys in various regions discussed endemic theory of sericulture in detail, then it formed systematic and mature viewpoint, and developed and perfected gradually. Due to multiple factors, the large-scale practices on the endemic theory of sericulture had encountered many difficulties. Withsericulture skill of modern times in western countries introducing,the modern sericulture skill less depended on endemic factors, modern scientific ideology gradually replaced the endemic theory of traditional sericulture.