Abstract: Urbanization is an inevitable product of social and economic development, and land ecological security is one of the important contents of the construction of ecological civilization. The acceleration of the process of urbanization has made land ecological security more and more concerned. Based on the entropy method and the coupling coordination degree model, this article analyzes the comprehensive evaluation index and coupling coordination degree of urbanization development and land ecological security in Anhui Province from 2000 to 2018, and uses the gray prediction model to predict. The results show that: (1) Anhui Province urbanization and the development level of land ecological security shows an obvious upward trend from 2000 to 2018, and it is the lagging type of land ecological security at this stage; (2) The comprehensive evaluation index of urbanization and land ecological security has steadily increased, the coupling degree is in an antagonistic state, and the two systems are coupled and coordinated, the type has gradually evolved from extreme imbalance and recession to primary coordinated development; (3) It is predicted that the degree of coordination between urbanization and land ecological security in Anhui Province will steadily increase from 2019 to 2023, and it may reach a level of good coordinated development in 2023. In order to promote the coordinated development of urbanization and land ecological security in Anhui Province, it is recommended to optimize the industrial structure, transform the economic development mode, increase environmental protection investment, and establish an integrated development concept.