Abstract: Agricultural development in the southwestern frontier region is the core driving force driving economic development in the frontier region. Brand building is the key and important problem in the strategy of agricultural enterprises in the southwestern frontier region. At present, there are not many influential agricultural enterprise brands in the southwest of the frontier, but the superior conditions such as high-quality germplasm resources and terrain and climate lay the foundation for building well-known brands of agricultural enterprises. This article analyzes quality, service and reputation, technological innovation, marketing and market promotion, and government support are the main influencing factors for the brand construction of agricultural enterprises in the southwestern borderland, and put forward development strategies for identifying brand positioning, cultivating brand awareness, and increasing investment in scientific research, in order to enhance the competitiveness of agricultural enterprises in the southwestern borderland reference.