Abstract: With the development of entrepreneurship education in China in full swing, the strengthening of entrepreneurship education research has become an inevitable requirement for the development of higher education. It is necessary to have a scientific method to study entrepreneurship education, and to make a whole from the perspective of teaching system construction. The author puts forward that the teaching system of entrepreneurship education mainly includes the target system, the curriculum system, the security system and the evaluation system. It is necessary to build an organic whole with each other and, in particular, to focus on the goal of cultivating innovative entrepreneurial talents and deepen entrepreneurship education curriculum design, teaching content, teaching mode and teaching method reform, the establishment of entrepreneurial teaching security system, strengthen the entrepreneurial education teachers, innovate entrepreneurship practice base construction, improve the education evaluation system of entrepreneurship, in order to achieve the purpose of innovation and entrepreneurship training.