Abstract: In order to analyze three influential factors ofcommunication, cooperation and knowledge sharing how to improve the cross functional coordination of research and development teams of Yunnan characteristic industry on new product efficiency,this paper combines with the research data and constructs structural equation model for new product development efficiency, the research and development teams of 10 characteristic industry enterprises in Yunnan province are surveyed through investigation and questionnaire.The research results show that communication has a positive direct impact on cooperation degree,knowledge sharing and new product development efficiency;knowledge sharing has a positive direct impact on cooperation degree;cooperation degree has a positive direct impact on new product development efficiency;knowledge sharing has not direct impact on new product efficiency, but indirectly impacts it through promoting cooperation degree.