Abstract: Based on the analysis of the present teaching situation of Building Water Supply and Drainage Engineering course, this paper focused on the teaching reform of curriculum under the guidance of CDIO engineering education model. The teaching objectives, teaching modes, safeguard measures and assessment methods of the course were studied and reformed in daily teaching, and the preliminary results are achieved. It provides useful experience and basis for the reform of the innovation education mode of undergraduate engineering courses, as well as personal comprehensive ability training.