Abstract: China is a unified multi-ethnic country, cultivating and practicing the socialist core values in frontier national regions is of great significance to enhance China's cultural soft power, to resist western cultural infiltration.Because of special geographical position, relatively backward economy caused by all kinds of reasons, diversity of living habits and religious beliefs, frontier minority areas is important and difficult in advancing the socialist core values. Therefore,this paper analyzes popularization of socialist core values in frontier national regions,by approach of contradiction analysis of marxist materialist dialectics, as well as put forward relevant suggestions and countermeasures.