Abstract: The effectiveness problem has been troubling the ideological and political theory course in college and university.This paper, on the basis of the demonstration, using the economics way of supply and demand to analyze the course of Mao zedong thought and socialism theory with Chinese characteristic system, it finds that: Because of large changes of the current college students comparing with college students in twentieth Century, under the conditions of seller's market supply, playing the leading role of the teacher is the key to improve the effectiveness.It needs teachers do some things to effectively improve the effectiveness of ideological and political theory course, it includes: improve theoretical foundation, capture the actual demand for students, strengthen the teachers' ability of social practice, establish scientific evaluation mechanism.Only in this way, can they improve effectiveness of ideological and political theory course.