Abstract: Aiming at the existing problems in the training process of intelligent manufacturing talents of mechanical specialty in local agricultural university, this paper explores the reform of talent education mode, through reforming the traditional training objective and reconstructing the curriculum structure of intelligent manufacturing, constructing the teaching mode based on intelligent manufacturing, exploring the teaching content adapting to the course system of intelligent manufacturing, construction of practical innovation ability training system, development of virtual simulation experiment system for professional practice teaching. By practice, students’ awareness of intelligent manufacturing and comprehensive ability have been significantly improved. At the same time, this research result has a certain reference value for other talents education mode reform.