Relationship of Visfatin and IGF-Ⅰ in Venous Blood with Calf Birth Weight

Purpose In order to explore the correlation between visfatin, IGF-Ⅰ in cow calf and cord venous blood and calf birth weight (CBW).Method 54 healthy Chinese Holstein cows, which experienced normal delivery, were used in the present study. The cows were grouped according to birth weight of their calves (group A: ≤ 40 kg, n=9; group B:40-45 kg,n=25; group C: ≥ 45 kg,n=20).Cow, calf and cord venous blood were collected respectively after delivery. ELISA was used to evaluate the level of visfatin and IGF-Ⅰ in serum, the correlation among them as well as correlation with CBW was analyzed.Result Visfatin and IGF-Ⅰ expressed in cow, calf and cord venous blood. With the increase in CBW, the visfatin in calf and cord venous blood of group A were significant higher those of group C (PPP>0.05). The visfatin and IGF-Ⅰ in cow, calf and cord venous blood had highly significant positive correlation with each other(PP>0.05), but had significant correlation between visfatin in calf venous blood (PPP>0.05); while visfatin and IGF-Ⅰ in calf venous blood had highly significant positive correlation with those in cord blood venous (PP>0.05).Conclusion There were visfatin and IGF-Ⅰ expressed in cow, calf and cord venous blood, visfatin and IGF-Ⅰ in calf and cord venous blood can affect CBW rather than those in cow venous blood; Visfatin and IGF-Ⅰ in cow, calf and cords venous blood had no significant differences between the male and the female calf respectively.