Synthesis and Insecticidal Activity of New Substituted Acylhydrazone Compounds

Taking p-chlorobenzoic acid, methanol, hydrazine hydrate, p-nitrobenzaldehyde, p-methoxybenzaldehyde and acetophenone as materials, p-nitrobenzaldehyde p-chlorobenzoyl hydrazone, p-methoxybenzaldehyde p-chlorobenzoyl hydrazone and acetophenone p-chlorobenzoyl hydrazone were synthesized in lab. Their structures were confirmed by 1HNMR, elemental analysis and the infrared spectrum. The insecticidal activities of target compounds were tested against Pieris rapae larvae in lab. The results showed that p-nitrobenzaldehyde p-chlorobenzoyl hydrazone had the strongest contact toxicity and stomach toxicity. Insecticidal activities of series of concentrations of p-nitrobenzaldehyde p-chlorobenzoyl hydrazone were tested against P.rapae and the EC50 of contact toxicity and stomach toxicity 24h after treatment were 497.85mg/L、287.01mg/L and 48h after treatment were 272.21mg/L and 145.75mg/L, respectively.