Effects of Rice Diangu No.2 on Blood Glucose and Blood Lipids in Rats

PurposeTo study the effect of feeding rice Diangu No.2 feed rich in resistant starch on the blood glucose and lipid metabolism in rats.

MethodsMale type II diabetic GK rats and Wistar rats at 12 months of age were used as test subjects, and the test group (fed with rice Diangu No.2 rat chow), control group (fed with rice Dianheyou 918 rat chow) and GK positive control group (fed with Dianheyou 918 rice rat chow and gavaged with metformin) were set up under suitable environmental conditions for six weeks, and the blood glucose and lipid-related indexes of each group were measured, compared and analyzed.

ResultsThe weekly fasting blood glucose, glycated serum protein content, blood glucose values at each time point and glucose tolerance, and the concentrations of total cholesterol, high-density lipoprotein and triglycerides were significantly lower in the test and positive control groups of GK rats than in the control group (P<0.05); and the concentration of low-density lipoprotein was lower than in the control group (P>0.05). Except the value of high-density lipoprotein/low-density lipoprotein, there was no significant difference between the groups of Wistar rats for each assay (P>0.05).

ConclusionRice Diangu No.2 can control blood glucose and lipids in GK rats better, but has no significant effect on blood glucose and lipids in Wistar rats.