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Wei LU, Wanfang SHAO, Fengmei LU, et al. The Preventive Effect of Suancha from De’ang Nationality on Non-alcoholic Fatty Liver[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2020, 35(1): 114-121. DOI: 10.12101/j.issn.1004-390X(n).201909029
Citation: Wei LU, Wanfang SHAO, Fengmei LU, et al. The Preventive Effect of Suancha from De’ang Nationality on Non-alcoholic Fatty Liver[J]. JOURNAL OF YUNNAN AGRICULTURAL UNIVERSITY（Natural Science）, 2020, 35(1): 114-121. DOI: 10.12101/j.issn.1004-390X(n).201909029
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The Preventive Effect of Suancha from De’ang Nationality on Non-alcoholic Fatty Liver

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    • Abstract
  • Purpose Suancha was the unique tea product from De’ang Nationality. Our aim was to study the effect of Suancha on the non-alcoholic fatty liver caused by exogenous dietary induction.
    Method Contrast with hepatoprotectants, the rats were given different does for 4 weeks, and then executed. The peripheral blood, blood lipid index, liver function index and antioxidant index were detected; the expression insulin growth factor (IGF-1) and cytochrome P4502E1 (CYP2E1) were studied; pathological observation and evaluation on liver tissue of rats were carried out.
    Result Suancha could effectively reduce the content of CHOL and TG in the serum of rats with non-alcoholic fatty liver, and increase the level of HDL-C; it could reduce the activity of AST and ALT in rat serum; it could increase enzyme activity level of GSH-Px and SOD in rat’s serum and liver; high-dose Suancha could improve liver tissue damage caused by lipid accumulation; Suancha could increase the expression of IGF-1 mRNA in liver tissue of test rats and inhibit the expression of CYP2E1 mRNA.
    Conclusion Suancha from De’ang Nationality has a positive effect on non-alcoholic fatty liver on rats.
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